Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 157 |
VP, Business Operations & Partnerships, Clinical Operations
Cambridge, Massachusetts
Overview The Vice President, Business Operations & Partnerships is a critical executive-level role responsible for defining, governing, and scaling the operating model that enables Alnylam's Pipeline Delivery organization to execute on clin...
13h
| Job Type | Full Time |
Senior Manager, Medical Writing
Cambridge, Massachusetts
OVERVIEW: The Senior Manager, Medical Writing will collaborate with project teams on the development of clinical documents in accordance with all applicable regulations, Good Clinical Practices, and Standard Operating Procedures (SOPs) and ...
13h
| Job Type | Full Time |
Associate Director, Regulatory Affairs
Cambridge, Massachusetts
Overview The Associate Director of Regulatory Affairs Strategy will serve as US Regional Lead or Global Regulatory Lead for our early/mid/late-stage CNS programs. The role will lead the regulatory strategy and facilitate submission of data ...
13h
| Job Type | Full Time |
Principal Associate Scientist, Target Validation
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking an experienced, highly motivated Principal Associate Scientist to validate therapeutic gene targets through in vitro and in vivo mechanistic studies to support discovery efforts for fut...
13h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Senior Manager, U.S. Payroll will own the end-to-end U.S. payroll function, ensuring accurate, compliant, and timely payroll processing for all U.S. employees. This role oversees the full payroll cycle, including data collectio...
13h
| Job Type | Full Time |
Associate Director, Market Insights
Cambridge, Massachusetts
Overview: The Associate Director of Market Insights will be responsible for the development and execution of primary and secondary market research plans to support the US TTR commercial priorities across patient audiences. This individual w...
13h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam's commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolon...
13h
| Job Type | Full Time |
Regional Business Director, TTR - Northern California
Cambridge, Massachusetts
Overview: We are looking for an experienced Regional Business Director (RBDs to support the promotion of AMVUTTRA (vutrisiran). The U.S. Food and Drug Administration (FDA) recently approved the supplemental New Drug Application (sNDA) for A...
1d
| Job Type | Full Time |
Associate Director, CMC Technology Delivery
Cambridge, Massachusetts
Overview Alnylam is seeking an experienced leader to serve as Associate Director, CMC Technology Delivery to lead the digital enablement and transformation of end-to-end Chemistry, Manufacturing and Controls (CMC). This role will execute di...
1d
| Job Type | Full Time |
Associate Director, Supply Chain Technology Delivery
Cambridge, Massachusetts
Overview Alnylam is seeking an experienced leader to serve as Associate Director, Supply Chain Technology Delivery to support the digital enablement of end-to-end clinical and commercial supply chain operations. This role will drive digital...
1d
| Job Type | Full Time |