Director, Veterinary Pathologist

Sarepta Therapeutics
United States, Ohio, Columbus
Jan 05, 2025
Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: Physical and Emotional Wellness Financial Wellness Support for Caregivers For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us The Importance of the Role The Director, Veterinary Pathologist will report to Head of Translational Biology and be based in Columbus, OH. He/She will primarily serve as Study Pathologist for GLP Toxicology studies and as a peer-reviewer for external toxicology studies. This Pathologist will collaborate closely with the Head of Non-Clinical Safety and associated study directors. This position will also serve as Study Pathologist for in-house non-GLP studies to support the research and development of Sarepta's portfolio. Additionally, he/she will work closely with the necropsy, histology, and morphometrics teams in supporting best practices for histopathology and digital pathology; including review of new staining techniques and image analysis algorithms, support for validation activities of fit-for-purpose digital image analysis methods and provide expert quality review of clinical and non-clinical histopathology images. The Opportunity to Make a Difference Serve as Onsite Study Pathologist in contributing to the design, macroscopic and microscopic examinations, interpretation, and reporting of GLP and non-GLP (exploratory, investigative, etc.) efficacy and toxicology studies conducted in-house and as needed, supervise necropsies. Serve as Peer-Review Pathologist on GLP and non-GLP toxicology studies conducted at CROs. Be a specialized resource for the histology and morphometrics team in developing and validating new staining techniques and digital image analysis algorithms Provide training, technical guidance and scientific leadership in necropsy and histopathology best practices to laboratory staff Serve as a resident subject matter expert in both in-house and outsourced investigative and toxicology studies and coordinate consultations with external experts in risk assessment of nonclinical pathology findings Evaluate and score in situ hybridization (e.g. RNAscope), IHC, IF, and special stains, as needed. Collaborate with other scientists on R&D-wide initiatives and research projects Additional pathology-related responsibilities as assigned More about You DVM with DACVP certification or equivalent required; MS/PhD preferred Minimum of 3 years of experience in macroscopic and microscopic examinations of small and large animal tissues in toxicology studies and in the interpretation and investigation of the significance of pathology findings in an industry or academic setting Expertise/experience in the neuromuscular and CNS field highly desirable Knowledge and experience in digital pathology is highly desirable Excellent verbal and written presentation and inter-personal skills Strong scientific writing and problem-solving skills Knowledge/experience in clinical pathology preferred #LI-TD1 What Now? We're always looking for solution-oriented, critical thinkers. So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-Onsite #LI-TD1 This position requires work on site at one of Sarepta's facilities in the United States. The targeted salary range for this position is $171,200 - $214,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.