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Senior Commercial Strategy and Planning Manager (Zanzalintinib)

Exelixis
paid holidays, sick time, 401(k)
United States, California, Alameda
Apr 24, 2026

SUMMARY/JOB PURPOSE (Basic purpose of the job):

The position will be accountable for contributing to cross-functional initiatives to advance the development of Zanzalintinib, Exelixis' oral multi-TKI in late-phase development. This position will provide critical information and advice to Exelixis leadership.

ESSENTIAL DUTIES/RESPONSIBILITIES:

  • Primarily responsible for delivering pipeline commercial analysis and strategic planning activities focused on Zanzalintinib, including:
    • Provide commercial assessment and develop revenue forecasts for potential indications to inform Ph3 Go/No-Go decisions and to support business planning
    • Plan and execute primary and secondary market research to support commercial opportunity assessment, revenue forecast assumptions, and address unknowns in new tumor types and indications
    • Develop treatment and competitive landscapes in key solid tumors to inform program development decisions
    • Drive Target Product Profile (TPP) development and refinement in partnership with Development
    • Provide comprehensive competitive intelligence to inform pipeline strategy and competitive positioning:
      • Monitor for competitor and disease landscape news, clinical developments, data releases, earnings releases, announcements, and other relevant disclosures
      • Generate alerts of key developments for stakeholders, including senior leadership
      • Attend relevant conferences and provide summaries of key presentations that contextualize data with clinical and scientific benchmarks
  • Work cross-functionally with Commercial, Clinical Development, Translational Medicine, Medical Affairs, and Finance functions to generate wholistic recommendations
  • Review clinical data for pipeline opportunities and assess competitive positioning and commercial implications
  • Determine the appropriate analyses required to answer key business questions and generate data driven recommendations
  • Provide and ensure the interpretation of complex analytical information to include Primary and Secondary Data, Forecasting, Competitive Intelligence, Scenario Planning, and other relevant sources of information and analysis
  • Manage third party vendors/contractors to oversee the execution of Market Research and Competitive Intelligence
  • Presentation of key deliverables to a broad range of stakeholders, including senior leadership

SUPERVISORY RESPONSIBILITIES:

  • No supervisory responsibilities.

EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS:

Education:

  • BS/BA degree in related discipline and 5 years of related experience; or
  • Masters in related discipline and 3 years of related experience; or
  • Ph.D. in related discipline; or
  • Equivalent combination of education and experience

Experience:

  • Previous experience in life sciences strategy consulting or pharma/biotech analytics is highly desirable
  • Previous new product evaluation experience is required
  • Prior oncology experience highly desired with specialty product experience as a minimum
  • Experience in developing cross-functional partnerships and collaborating with clinical stakeholders

Knowledge, Skills and Abilities:

  • Proficiency in qualitative and quantitative primary research methods
  • Proficiency in evaluating scientific and clinical literature to develop a perspective on evolving treatment landscapes and oncology markets
  • Strong foundation in patient-based forecasting and quantitative modeling methodologies
  • Demonstrates strong collaboration skills and ability to be a strategic thought partner; networks with key contacts outside own area of expertise
  • Ability to frame critical business questions, identify information needs to answer those questions, and determine where to best search for primary and secondary information sources
  • Knowledge of key market-shaping activities and how data can support success
  • Ability to navigate uncertainty and apply structured thinking and decision-making frameworks to complex business questions
  • Effective presentation and communication skills, both verbal and written
  • Excellent organizational, project management and problem-solving skills

#LI-JP1

If you like wild growth and working with happy, enthusiastic over-achievers, you'll enjoy your career with us!

Our compensation reflects the cost of labor across severalU.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this positionis $184,000 - $261,000 annually. The base pay range may take into account the candidate's geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate's geographic region, job-related knowledge, skills, experience and internal equity, among other factors. In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

DISCLAIMER
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

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