Post Doctoral Fellow

Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation's oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.

The Genomics & Bioinformatics Core Facility at Saint Louis University is seeking a talented, self-motivated Postdoctoral Fellow to support the daily operations of the core and contribute to the collaborative research projects we support across the SLU community.

Our facility assists investigators with single cell transcriptomic studies using 10X Genomics platforms, epigenomic profiling with Epicypher technologies and bulk RNA-seq experiments performed on Illumina platforms. We are engaged in a wide range of human health-related research, including studies of immune responses in autoimmune and other disease settings, kidney injury and development, and responses to cancer therapy, among others. As a small highly collaborative team, we partner closely with researchers to support their projects from beginning to end including in experimental design, library preparation, data analysis, and publication.

This position involves both wet-lab and computational work. The fellow will apply cutting-edge genomics technologies to collaborative projects and manage the day-to-day operations of the core. Responsibilities include general lab management, cell and tissue handling, NGS library preparation, and data analysis using industry standard command-line tools and R based pipelines for bulk and single cell genomics.

The ideal candidate is highly organized, detail-oriented, and adaptable, with strong communication skills and the ability to serve a diverse research community. This role offers the opportunity to work in a dynamic, interdisciplinary environment with mentorship, professional development, and resources to support your growth and success.

Knowledge, Skills, Abilities, and Personal Characteristics

• Strong laboratory skills in molecular biology, tissue culture, NGS library preparation, and other standard bench techniques.

• Expertise in transcriptomic and/or epigenomic data analysis with a solid understanding of statistics and familiarity across multiple biological fields of study.

• Exceptional organizational skills with strong attention to detail in data management, record keeping, and laboratory operations.

• Ability to maintain accurate, complete and well-organized records and reports in both written and electronic formats.

• Excellent scientific writing and verbal communication skills.

• Strong analytical, reasoning, and problem-solving abilities, with demonstrated independence and skill in troubleshooting scientific challenges.

• Proven ability to train and mentor researchers in techniques and analysis.

• Capacity to adapt to a fast-paced research environment and rapidly move between different research projects at various stages

Job Duties and Responsibilities

• Support researchers with NGS projects, including maintaining supplies and reagents, isolating cells, preparing NGS libraries, performing standard QC, and preparing libraries for sequencing.

• Implement algorithms and computational tools for omics-based data analysis

• Develop and apply data management solutions that aid in the storage, use, and sharing of large data sets

• Provide consultation and technical assistance to core facility users, including troubleshooting experimental and analytical issues.

• Independently evaluate research findings and communicate results to the laboratory team, principal investigator, and collaborators.

• Prepare and present oral reports at laboratory meetings and other group discussions.

• Maintain accurate records of experimental protocols and results; monitor data to ensure consistency and reliability.

• Manage project-related records including usage tracking, billing documentation, and supply inventory.

• Collaborate with Director to update and organize laboratory protocols and standard operating procedures.

• Ensure that laboratory conditions and equipment are properly cleaned, maintained, and operated in accordance with established procedures.

• Adhere to ethical standards in research, including regulations governing human subjects and animal care and use.

• Maintain compliance with good laboratory practice and ensure proper documentation of research activities.

• Follow all applicable University policies, procedures, and regulatory requirements.

Required Qualifications

• Ph.D. in biological sciences or related field, with experience in transcriptomic and/or epigenomic research and broad knowledge of laboratory techniques with preferred experience in specialized areas such as single cell transcriptomics.

Function

Scheduled Weekly Hours:

Saint Louis University is an equal opportunity/affirmative action employer. All qualified candidates will receive consideration for the position applied for without regard to race, color, religion, sex, age, national origin, disability, marital status, sexual orientation, military/veteran status, gender identity, or other non-merit factors. If accommodations are needed for completing the application and/or with the interviewing process, please contact Human Resources at 314-977-5847.