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Director, Supply Chain and CMO Outsourcing, Procurement

Sarepta Therapeutics
United States, Massachusetts, Cambridge
215 First Street (Show on map)
Dec 09, 2025
Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: Physical and Emotional Wellness Financial Wellness Support for Caregivers For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us The Importance of the Role The Director, Supply Chain and CMO Procurement builds, operationalizes, and executes strategic sourcing strategies for CDMO/CMO and Testing Labs to support our Manufacturing, Quality, Process Development, and Supply Chain organization. This role also integrates supplier selection, negotiation and contracting, and supplier relationship management with consolidation of spend in partnership across Supply Strategy & Planning, Quality Assurance, Quality Control, Process Development Global Manufacturing and Global Supply Chain. The role interface closely with business partners to understand business priorities and needs, and in turn, define specific initiatives to support Sarepta business priorities and growth. The Opportunity to Make a Difference Business Partnering Collaborates and builds productive relationships with Supply Chain, Quality, Process Development and Manufacturing business partners and stakeholders while developing relationships with external key suppliers/ CDMO/CMO to identify opportunities to gain efficiencies, drive cost savings, proactively respond to business needs, and reduce risk while fulfilling business requirements. Partnering with stakeholders to align prioritization and lead execution. Category Management Support the development category and sourcing strategies for siRNA program development and clinical material supply, and commercial lunch readiness. Identify potential CDMO/CMO for new programs and ensure right-size capacity for programs/products at different stages. Lead category strategy implementation as well as value creation initiatives in support of business priorities and deliver cost savings in Drug Substance, Drug Product, Pack & Label, and domestic and internal Distribution. Supports the business team with identification of all applicable risks as part of the Sourcing process, including coordination with the key business stakeholder to properly assess and develop mitigation plans, where necessary. Ensures accurate reporting of Procurement key performance measures (operational metrics, savings, quality, customer service, etc.) for the category and tracks ROI. Identify COGS savings opportunities and drive implementation. RFx and Contract Negotiation Leads supplier identification / selection and implement RFx activities. Lead negotiations of clinical and commercial supply agreements with key suppliers/CMOs/CMP Labs, and drive prioritization alignment across Business, Finance and Legal and external partners. Implementing RFx activities. Preparing and implementing advanced negotiation strategies. Manage complex negotiations on price and terms, partnering with stakeholders and Legal to negotiate and finalize agreements. SRM Manages the Supplier/CMO Performance/Relationship Management process and ensures performance and accountability are tracked and improved. Maximizing values from our supplier relationships. Develop and maintain strong vendor relationships to ensure continuity of supply and innovation in processes. More about You 10+ years of demonstrated relevant Sourcing & Procurement experience in QC GMP Testing/Supply Chain/CMC sourcing and experience in RNA and siRNA manufacturing or chemistry CMO outsourcing is preferred. Demonstrated understanding of GMP requirements and international supply chain complexity Experience working with stakeholders/partners at all levels, across the organization. In-depth strategic and operational procurement experience with knowledge of category management. Outstanding communication. Strong negotiation skills. Strong business acumen and financial analysis capabilities; ability to develop solid business cases to demonstrate the value proposition to move forward with project investment. Advanced skills with Microsoft Office Applications; Word, Excel, Powerpoint, and Outlook. You will be expected to work on site at one of Sarepta's facilities in the United States. This is not a remote role What Now? We're always looking for solution-oriented, critical thinkers. So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-Onsite #LI-CM1 This position requires work on site at one of Sarepta's facilities in the United States. The targeted salary range for this position is $180,000 - $225,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.